Description
Product Characteristics: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of IRAK3 in human serum, plasma, tissue homogenates, cell lysates, cell culture supernates.
Target Information: This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]